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The Alpha and Beta of GSK-3s – first in the Strange but Powerful Molecules...
The Molecules that Play Dr. Jeckel and Mr. Hyde in Aging, Alzheimer’s Disease, and Type II Diabetes By James P Watson, with summary and contributions from Vince Giuliano Introduction – GSK-3s – The...
View ArticleThe Prospects that Emerging Science Offers Us for Long Healthy Lifespans –...
By Vince Giuliano I rarely hesitate to talk about exciting research developments reported in this blog with my friends. However, only a few people in our local community of Wayland Massachusetts have...
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NAD+ an emerging framework for life extension — Part 1: The NAD World
By Vince Giuliano with inputs from by James P. Watson Accelerated by the publication in December 2013 of a seminal paper by David Sinclair and his US and Australian colleagues(ref), there has been...
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NAD+ an emerging framework for life health and life extension — Part 2:...
By James P Watson with contributions and assistance by Vince Giuliano This is Part 2 of what will likely be a three or four-part series of blog entries related to the metabolic cofactor NAD+. The Part...
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Digital health – health and fitness wearables, apps and platforms –...
By Vince Giuliano with inputs and assistance from Melody Winnig and James P Watson INTRODUCTION The consumer electronics industry is giving a tremendous boost to public and individual health – perhaps...
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Digital health – health and fitness wearables, Part 2: looking for practical...
By Vince Giuliano This entry is different from any other published so far in this blog – it describes an original research experiment rather than characterizing a whole area of research or being an...
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Digital health – health and fitness wearables, Part 3: Heart Rate...
By James P Watson with contributions and editorial assistance by Vince Giuliano This is the third blog entry related to electronic wearable devices capable of making personal behavioral and physical...
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A simple, comprehensive plan to prevent or reverse Alzheimer’s Disease and...
By James P Watson, with contributions and editorial assistance by Vince Giuiliano INTRODUCTION AND OVERALL PRINCIPLES This is the first of a pair of blog entries concerned with dementias –...
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30 Major Factors that Control SIRT1 Expression, SIRT1 Activity, and...
By James P Watson with comments and editorial assistance by Vince Giuliano Introduction by Vince Giuliano: This is the third blog entry in the series NAD+ an emerging framework for health and life...
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Part 4 of the NAD world: the NQ01 gene, the Warburg effect, SIRT 1 and...
By James P Watson with contributions and editorial assistance by Vince Giuliano This Part 4 blog entry goes even further into the extended NAD story, examining important subtopics: The ratio NAD+/NADH...
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Digital Health Part 4: Heart rate stress biomarkers derivable from smart...
By Vince Giuliano This blog entry focuses deeper on personal research I have been doing on specific constitutional stress biomarkers derivable from measurements by a smart watch, a Basic Peak in my...
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The top 21Benefits of Meditation
By James P Watson, with editorial assistance and comments by Vince Giuliano and Melody Winnig Initial comments – by Vince Giuliano This blog entry is about thoroughly documented health and possible...
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G-qaudruplexes
By James P Watson with editorial help and selected contributions by Vince Giuliano Image source Human telomeric G-quadruplex structure Introduction by Vince Giuliano If you are new to G-quadraplexes,...
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Transposable DNA elements – Part 1: basics and importance
By Vince Giuliano, inspired by interaction by James P. Watson This is the first blog entry in a three-part series concerned with transposable DNA entries (TEs). It focuses on basics of what TEs are,...
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Transposable DNA elements –- Part 2: The Self-copy Machines in Your Genes
By James P Watson with editorial and some content contribution by Vince Giuliano This is the second blog entry in a three-part series concerned with transposable DNA entries (TEs). The Part 1 entry...
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Transposable DNA elements – Part 3 TEs and and other key mechanisms of...
By Vince Giuliano, with inspiration by Jim Watson Image source: “These clusters of cells are 1 billion years old, the oldest to appear in freshwater/land ecosysems Credit: Oxford...
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Hutchinson-Gilford Progeria Syndrome – a disease of accelerated aging due to...
By James P Watson with editorial assistance and contributions from Vince Giuliano I. WHY YOU SHOULD BE INTERESTED IN HUTCHINSON-GILFORD PROGERIA SYNDROME (HGPS) Summary: HGPS is a major clue to...
View Article2016 meeting of the International Dose-response Society
Note by Vince Giuliano As has been the case in several previous years, I intend to attend the 2016 annual meeting of the International Dose-response Society which will be held on the Campus of the...
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Coming in this blog
By Vince Giuliano and James P Watson This entry signals some intended changes in our blogging approach and lists some blog entries we plan to publish soon. A. Changes in blogging approach We expect to...
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Part 5 of the NAD world: the conflicting roles of NAMPT – inflammation or...
By James P Watson with commentary and assistance by Vince Giuliano Introduction by Vince Giuliano This blog entry relates another important story of what goes on in the NAD world. This is also the...
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