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The pivotal role of Nrf2. Part 3 – Part 3 – Is promotion of Nrf2 expression a...

By Vince Giuliano This is the third of three blog entries relating to the Nrf2 pathway.  The first blog entry The pivotal role of Nrf2. Part 1 – a new view on the control of oxidative damage and...

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Gut microbiota, probiotics, prebiotics and synbiotics – keys to health and...

By Vince Giuliano To take care of your own health you have to take care of about a hundred trillion other living entities.  Each of us is in close relationship with that many micro-organisms belonging...

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Blue light, sleep, mental alertness and health

By Vince Giuliano We are being exposed to a lot more blue and ultraviolet light in recent years, especially at night.  This is due to 1. fluorescent bulbs replacing incandescent bulbs in homes and...

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Focus on phytosubstances – amazing properties of epimedium and icariin

By Vince Giuliano Icariin is the active flavinoid substance in the traditional Chinese medicinal herb Epimedium brevicornum Maxim.  Icariin can be derived from several species of plants in the...

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New, emerging and potential treatments for cancers: Part 1 – focus on the...

By Vince Giuliano This is the first post in a three-part series concerned with new, emerging and potential future treatments for cancers.  This Part 1 post is concerned mainly with interventions that...

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Epigenetic Mechanisms of Long-term Memory

By Victor We all know that we are able to store sensory experiences for later recall; in a very real sense, collection of memories acquired during life represents our personal identity.  However, the...

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New, emerging and potential treatments for cancers: Part 2 – focus on...

By Vince Giuliano This is the second post in a three-part series concerned with new, emerging and potential future treatments for cancers.  This Part 2 post is concerned with anti-cancer drug and other...

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New, emerging and potential treatments for cancers: Part 3 – selected...

By Vince Giuliano This is the third post in a three-part series concerned with new, emerging and potential future treatments for cancers.  This Part 3 post relates to a vast and largely unknown area...

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Chronic rhinosinusitis, MRSA, biofilms and manuka honey

By Vince Giuliano Longevity is the art of not dying.  This art in turn draws heavily on the various arts of staying well.  Chronic rhinosinusitis (CRS), though not usually a life-threatening illness in...

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Symposium on Cell Signaling, Inflammation and Aging

By Vince Giuliano I am an invited speaker at a symposium in Las Vegas June 5-6, on Cell Signaling, Inflammation and Aging sponsored by the Hawaii Institute of Molecular Education.  The symposium is...

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Prostate cancer – epigenetic factors, the role of Nrf2, cancer stem cells and...

By Vince Giuliano There have been several important research findings in recent years relating to prostate cancer, ones that are transforming our views of the disease process and offering hopes for...

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Important recent research on cancer stem cells in lung cancers

Worldwide, lung cancer is the most lethal malignancy, one responsible for more than 1.3 million deaths annually.  The deaths are most-often associated with rapid spread (metastasis) of the lung cancer...

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Telomerase update –arguments for and against using telomere extender supplements

By Vince Giuliano In past blog entries and in my treatise I have explained how I was an early adapter at taking telomerase extenders like astrogaloside4 and cycloastragenol, and why, later as a result...

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Guest commentary – Robert Pappas on de Grey – Blakemore Oxford University...

The following was written by my colleague Robert Pappas on a debate that took place recently at Oxford University between two prominent British scientists on “defeating aging.”  The writing largely...

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Free conference webcast – Symposium on Cell Signaling, Inflammation and Aging...

I will be in Las Vegas presenting at one session and moderating another at this symposium.  As mentioned in an earlier blog, the symposium is sponsored by the Hawaii Institute of Molecular Education...

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Insights into the epigenetics and rejuvenation of adult stem cells –...

By Vince Giuliano Recent research indicates a brighter possibility for extraordinary human longevity – healthy lives extending perhaps to hundreds of years.  The general approach is one I have been...

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A stem cell cure for Parkinson’s Disease – so close and yet so far away

Article and image by Vince Giuliano Stem cell injections have been shown to improve symptoms of Parkinson’s Disease (PD) in a rat model, essentially providing a “cure” for the disease.  This is after...

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Observations on the evolution of evolution

This blog entry expresses some of my less-orthodox opinions on the nature of human evolution, how we got to this point and where we are going as a species.  It builds on the arguments set forth in...

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Phytosubstances – focus on Andrographis, an old medicine with many possible...

By Vince Giuliano This blog entry looks at recent research on Andrographis - a herbal substance that is a staple of traditional Chinese, Indian and South Asian medicine.  It has been used for centuries...

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Adaptogens Part 1 – video blog

By Vince Giuliano This and the Part 2 blog entry are pursuant to one of the key themes of this blog –  the use of phyto substances to promote health and longevity.  Specifically, they are about...

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